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Børn i Vestafrika

Studier fra Vestafrika viser at Calmette udover at beskytte mod tuberkulose også har en ikke-specifik effekt, der nedsætter dødelighed og sygelighed blandt små børn i de første leveår: 

(1) Roth A, Jensen H, Garly ML, Djana Q, Martins CL, Sodemann M, et al. Low birth weight infants and Calmette-Guérin bacillus vaccination at birth: community study from Guinea-Bissau. Pediatric Infectious Disease Journal 2004 Jun;23(6):544-50.

(2) Aaby P, Jensen H, Gomes J, Fernandes M, Lisse IM. The introduction of diphtheria-tetanus-pertussis vaccine and child mortality in rural Guinea-Bissau: an observational study. International Journal of Epidemiology 2004 Apr;33(2):374-80.

(3) Aaby P, Jensen H, Garly ML, Bale C, Martins C, Lisse I. Routine vaccinations and child survival in a war situation with high mortality: effect of gender. Vaccine 2002 Nov 22;21(1-2):15-20.

(4) Kristensen I, Aaby P, Jensen H. Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa [In Process Citation]. BMJ 2000 Dec 9;321(7274):1435-9.

(5) Aaby P, Vessari H, Nielsen J, Maleta K, Benn CS, Jensen H, et al. Sex differential effects of routine immunizations and childhood survival in rural Malawi. Pediatric Infectious Disease Journal 2006 Aug;25(8):721-7.

(6) Velema JP, Alihonou EM, Gandaho T, Hounye FH. Childhood mortality among users and non-users of primary health care in a rural west African community. International Journal of Epidemiology 1991 Jun;20(2):474-9.

(7) Garly ML, Martins CL, Balé C, Baldé MA, Hedegaard KL, Gustafson P, et al. BCG scar and positive tuberculin reaction associated with reduced child mortality in West Africa: A non-specific beneficial effect of BCG? Vaccine 2003;21:2782-90.

(8) Roth A, Gustafson P, Nhaga A, Djana Q, Poulsen A, Garly ML, et al. BCG vaccination scar associated with better childhood survival in Guinea-Bissau. International Journal of Epidemiology 2005 Jun;34(3):540-7.

(9) Roth A, Sodemann M, Jensen H, Poulsen A, Gustafson P, Weise C, et al. Tuberculin reaction, BCG scar, and lower female mortality. Epidemiology 2006 Sep;17(5):562-8.

(10)  Aaby P, Shaheen SO, Heyes CB, Goudiaby A, Hall AJ, Shiell AW, et al. Early BCG vaccination and reduction in atopy in Guinea-Bissau. Clinical and Experimental Allergy 2000 May;30(5):644-50.

 

Sidst redigeret 10. september 2012

Calmette-studiet

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Hovedansvarlig for Calmette-studiet

Lone Graff Stensballe
Børnelæge, ph.d.
Børnemodtagelsen 4064
BørneUngeKlinikken
Rigshospitalet
Juliane Maries Vej
2100 København Ø

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